Basic Information
VIS ID
TVIS44006107
Fusion event
HTLV-1-MINK1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.2
Reference genome
End
4747024/4843729 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-1301-3p ; hsa-mir-760 ; hsa-mir-744-5p ; hsa-mir-18a-3p ; hsa-mir-186-5p ; hsa-mir-222-3p ; hsa-mir-92a-3p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-20b-5p ; hsa-mir-520e ; hsa-mir-520f-3p ; hsa-mir-520a-3p ; hsa-mir-526b-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-519d-3p ; hsa-mir-520d-3p ; hsa-mir-302e ; hsa-mir-3646 ; hsa-mir-3662 ; hsa-mir-15b-3p ; hsa-mir-625-5p ; hsa-mir-1275 ; hsa-mir-3179 ; hsa-mir-3180-3p ; hsa-mir-3196 ; hsa-mir-3202 ; hsa-mir-3180 ; hsa-mir-4665-5p ; hsa-mir-4747-5p ; hsa-mir-5196-5p ; hsa-mir-6740-5p ; hsa-mir-6783-5p ; hsa-mir-6816-5p ; hsa-mir-7109-5p ; hsa-mir-487b-3p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-6739-5p ; hsa-mir-149-3p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-1321 ; hsa-mir-583 ; hsa-mir-1538 ; hsa-mir-4745-3p ; hsa-mir-671-5p ; hsa-mir-1247-3p ; hsa-mir-5572 ; hsa-mir-4260 ; hsa-mir-450a-2-3p ; hsa-mir-3942-3p ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-3160-5p ; hsa-mir-3185 ; hsa-mir-4796-3p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-1291 ; hsa-mir-1296-3p ; hsa-mir-194-3p ; hsa-mir-214-3p ; hsa-mir-3173-5p ; hsa-mir-3619-5p ; hsa-mir-424-5p ; hsa-mir-4291 ; hsa-mir-4519 ; hsa-mir-497-5p ; hsa-mir-6752-3p ; hsa-mir-6775-3p ; hsa-mir-6799-3p ; hsa-mir-6838-5p ; hsa-mir-761 ; hsa-mir-922
Nearest miRNA
hsa-mir-1253/Upstream/2095547; hsa-mir-10226/Downstream/125973;
Upstream sequence
GGTTGGAATAAGAACCGtaatgaacacttactgtgcagtaggttctttccttctgtaatctcattgtccctcacaagaaccctttgaggtggacaatatt
Downstream sequence
atcctcatttgcaagatgaagaaaccaaagcttacagaaattaacttggaagttaagtaacttgcctgaggttggacagccagtaagcagcagagcccac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate