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TVIS44006107
Basic Information
VIS ID
TVIS44006107
Fusion event
HTLV-1-MINK1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
4747024/4843729 (Hg38)
End
4747024/4843729 (Hg38)
Orient
-
Location type
Intronic
Target gene
MINK1
miRNAs that regulate target gene
hsa-mir-1301-3p
;
hsa-mir-760
;
hsa-mir-744-5p
;
hsa-mir-18a-3p
;
hsa-mir-186-5p
;
hsa-mir-222-3p
;
hsa-mir-92a-3p
;
hsa-mir-15a-5p
;
hsa-mir-16-5p
;
hsa-mir-15b-5p
;
hsa-mir-195-5p
;
hsa-mir-17-5p
;
hsa-mir-20a-5p
;
hsa-mir-93-5p
;
hsa-mir-106a-5p
;
hsa-mir-106b-5p
;
hsa-mir-302a-3p
;
hsa-mir-302b-3p
;
hsa-mir-302c-3p
;
hsa-mir-302d-3p
;
hsa-mir-372-3p
;
hsa-mir-373-3p
;
hsa-mir-20b-5p
;
hsa-mir-520e
;
hsa-mir-520f-3p
;
hsa-mir-520a-3p
;
hsa-mir-526b-3p
;
hsa-mir-520b
;
hsa-mir-520c-3p
;
hsa-mir-519d-3p
;
hsa-mir-520d-3p
;
hsa-mir-302e
;
hsa-mir-3646
;
hsa-mir-3662
;
hsa-mir-15b-3p
;
hsa-mir-625-5p
;
hsa-mir-1275
;
hsa-mir-3179
;
hsa-mir-3180-3p
;
hsa-mir-3196
;
hsa-mir-3202
;
hsa-mir-3180
;
hsa-mir-4665-5p
;
hsa-mir-4747-5p
;
hsa-mir-5196-5p
;
hsa-mir-6740-5p
;
hsa-mir-6783-5p
;
hsa-mir-6816-5p
;
hsa-mir-7109-5p
;
hsa-mir-487b-3p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-6739-5p
;
hsa-mir-149-3p
;
hsa-mir-6733-5p
;
hsa-mir-3153
;
hsa-mir-423-5p
;
hsa-mir-3184-5p
;
hsa-mir-6754-5p
;
hsa-mir-4441
;
hsa-mir-4270
;
hsa-mir-4739
;
hsa-mir-4756-5p
;
hsa-mir-1321
;
hsa-mir-583
;
hsa-mir-1538
;
hsa-mir-4745-3p
;
hsa-mir-671-5p
;
hsa-mir-1247-3p
;
hsa-mir-5572
;
hsa-mir-4260
;
hsa-mir-450a-2-3p
;
hsa-mir-3942-3p
;
hsa-mir-6803-5p
;
hsa-mir-6751-5p
;
hsa-mir-5010-5p
;
hsa-mir-4525
;
hsa-mir-3160-5p
;
hsa-mir-3185
;
hsa-mir-4796-3p
;
hsa-mir-548ah-5p
;
hsa-mir-3609
;
hsa-mir-1291
;
hsa-mir-1296-3p
;
hsa-mir-194-3p
;
hsa-mir-214-3p
;
hsa-mir-3173-5p
;
hsa-mir-3619-5p
;
hsa-mir-424-5p
;
hsa-mir-4291
;
hsa-mir-4519
;
hsa-mir-497-5p
;
hsa-mir-6752-3p
;
hsa-mir-6775-3p
;
hsa-mir-6799-3p
;
hsa-mir-6838-5p
;
hsa-mir-761
;
hsa-mir-922
Nearest miRNA
hsa-mir-1253/Upstream/2095547; hsa-mir-10226/Downstream/125973;
Nearest TSS
ENST00000595228/Upstream/10108;
ENST00000572629/Downstream/40740;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/9924
,
chr17-CpG: 238/Downstream/55241
Upstream sequence
GGTTGGAATAAGAACCGtaatgaacacttactgtgcagtaggttctttccttctgtaatctcattgtccctcacaagaaccctttgaggtggacaatatt
Downstream sequence
atcctcatttgcaagatgaagaaaccaaagcttacagaaattaacttggaagttaagtaacttgcctgaggttggacagccagtaagcagcagagcccac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL103
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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