Basic Information
VIS ID
TVIS44006141
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
GRCh37/hg19
Start
220508444/219643722 (Hg38)
End
220508444/219643722 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10b/Upstream/94575; hsa-mir-1244-1/Downstream/262780;
Nearest TSS
ENST00000437798/Upstream/10376; ENST00000597288/Downstream/1368;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/15657, chr2-CpG: 260/Downstream/1927288
Nearby gene
SLC4A3(+1742) ;
Upstream sequence
GAACAAAGTCAAGGTCAAACGCAAAACCTAGAAGGGACATGTGCAGAGAAGATTCCAAACAGAGATGTCAGGGGCCTCTCAGACAAGTTTGGTTGAGAGG
Downstream sequence
CTTTGCATATGAGAACCCTGGTTCCTTCCTAGAGTCCTGCTTCTCCTTGCGGGCCCGGATGCAGGAAAGGCTCCCCTGTTTGGTCTCGGGGATTCCTAGA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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