Basic Information
VIS ID
TVIS44006182
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
19441594/19441485 (Hg38)
End
19441594/19441485 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA5E
Nearest miRNA
hsa-mir-10397/Upstream/2285493; hsa-mir-103a-1/Downstream/12494617;
Nearest TSS
ENST00000502646/Upstream/299139; ENST00000513573/Downstream/37151;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/1785871, chr5-CpG: 45/Downstream/863968
Upstream sequence
TGCACATGTGCAAGTCTACCTACTAAATAAACTTCTTTGTCCTACGAGAGGTTTGCAGTACAGCCATTTTGAAGTTCAAGCTTTGAAAAAAAATGCAAGG
Downstream sequence
GCAAGGACCAGAGAAGAAGGCTAGGTGGAGACCTTTTACACCCATCAAAGTAAAGAAAGTTTAGTTTGATTGAGTCTTTGATTTTTACCTTCTCTTACTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate