Basic Information
VIS ID
TVIS44006203
Fusion event
HTLV-1-LOC105378031 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
142286944/141965807 (Hg38)
End
142286944/141965807 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105378031
Nearest miRNA
hsa-mir-10398/Upstream/1281924; hsa-mir-1202/Downstream/9136868;
Nearest TSS
ENST00000381078/Upstream/518796; ENST00000454401/Downstream/110115;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/2590366, chr6-CpG: 46/Downstream/122529
Nearby gene
NMBR(-109801) ;
Upstream sequence
taatttatgaaacatcatccttcctgttgttccaaccaaaaacactgaaaccattctttactcttttatttttctcaattatcacatcaaattaatcagg
Downstream sequence
aaatctttttgattattttaaaaaacatatccaaaatggaccacttatcacctctgttgccactagcctgacgtgagtggccagtatcagtcttgtcgac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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