Basic Information
VIS ID
TVIS44006220
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.21
Reference genome
GRCh37/hg19
Start
130050398/129038152 (Hg38)
End
130050398/129038152 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1204/Upstream/887964; hsa-mir-10400/Downstream/445905;
Nearest TSS
ENST00000518652/Upstream/72151; ENST00000519048/Downstream/203098;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1188174, chr8-CpG: 122/Downstream/900974
Nearby gene
LINC00977(No orient, 178315)
Upstream sequence
gagatgccattgcatcactgttagaacagctaaaatcaaagatattgacaataccaaatacctctgagaatatggaacaacaggaactctcattcattgc
Downstream sequence
tcgtggggaaacaaattttgggaaacagattagctgtttcttacaaagctaaacataagcatatgctgtcattgcttttctaggtatttacctaaatgaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate