Basic Information
VIS ID
TVIS44006239
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p15.32
Reference genome
GRCh37/hg19
Start
4876262/4876149 (Hg38)
End
4876262/4876149 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-4277/Upstream/3167281; hsa-mir-10397/Downstream/1951704;
Nearest TSS
ENST00000502646/Upstream/9628; ENST00000507599/Downstream/94276;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/9632, chr5-CpG: 148/Downstream/263179
Nearby gene
LOC105374629(-7934) ;
Upstream sequence
CACCTCATATGTACCTGGCTCTGCCCCTTTAGCACCAAGCAGAAGACCTGTCAGGTATCAGGTGCTCAGTGCAGGCTTTTCCATGTGAGACATCTTCTCG
Downstream sequence
GCCAGGGCCCTCATGAGAGTGAAGCTGCAAGAAGAATTGAGGGCTCTGTCAGCAAGGAAAGCAACTATGCTAGACCTCCCTGTGAGCTACTCTGAGGGTG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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