Basic Information
VIS ID
TVIS44006270
Fusion event
HTLV-1-chr13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
34833489/34259352 (Hg38)
End
34833489/34259352 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA13A
Nearest miRNA
hsa-mir-2276/Upstream/10096848; hsa-mir-1267/Downstream/5404682;
Nearest TSS
ENST00000623511/Upstream/428600; ENST00000605909/Downstream/88691;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/440996, chr13-CpG: 79/Downstream/682882
Nearby gene
LINC00457(No orient, 176102)
Upstream sequence
ATGTCACCAATCTTGCCCTTAATGCATTACGGCAGGACATGATGGAACATTAGTAGAGTGCAGTAGTGCACATTTGGAAAAAGAATGAACATGAAATTTG
Downstream sequence
GTAACACTATCTTATCAGTTGAATTTAAAATGAATATTAATCTTGCTTCTCTGGCAGAGGAACAGATGAATCAATGAAATATTTTACTAGATGCTGTGGG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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