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TVIS44006307
Basic Information
VIS ID
TVIS44006307
Fusion event
HTLV-1-BCL2L1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
30305942/31718139 (Hg38)
End
30305942/31718139 (Hg38)
Orient
+
Location type
Intronic
Target gene
BCL2L1
miRNAs that regulate target gene
hsa-mir-491-5p
;
hsa-let-7g-5p
;
hsa-let-7c-5p
;
hsa-mir-122-5p
;
hsa-mir-30a-5p
;
hsa-mir-484
;
hsa-mir-23b-3p
;
hsa-mir-133a-3p
;
hsa-mir-218-5p
;
hsa-mir-6858-5p
;
hsa-mir-4689
;
hsa-mir-1287-3p
;
hsa-mir-525-5p
;
hsa-mir-520a-5p
;
hsa-mir-198
;
hsa-mir-4710
;
hsa-mir-6797-5p
;
hsa-mir-1249-5p
;
hsa-mir-7854-3p
;
hsa-mir-6133
;
hsa-mir-6130
;
hsa-mir-6129
;
hsa-mir-6127
;
hsa-mir-4510
;
hsa-mir-4419a
;
hsa-mir-4784
;
hsa-mir-3150b-3p
;
hsa-mir-455-3p
;
hsa-mir-4779
;
hsa-mir-4257
;
hsa-mir-575
;
hsa-mir-4676-5p
;
hsa-mir-6858-3p
;
hsa-mir-4749-3p
;
hsa-mir-587
;
hsa-mir-4313
;
hsa-mir-324-3p
;
hsa-mir-1913
;
hsa-mir-1976
;
hsa-mir-6747-3p
;
hsa-mir-6727-3p
;
hsa-mir-4722-3p
;
hsa-mir-361-3p
;
hsa-mir-4691-3p
;
hsa-mir-449b-3p
;
hsa-mir-133b
;
hsa-mir-608
;
hsa-mir-34a-5p
;
hsa-mir-326
;
hsa-let-7a-2-3p
;
hsa-let-7g-3p
;
hsa-mir-1207-5p
;
hsa-mir-1233-5p
;
hsa-mir-1251-5p
;
hsa-mir-1265
;
hsa-mir-1273h-5p
;
hsa-mir-1289
;
hsa-mir-1321
;
hsa-mir-149-3p
;
hsa-mir-184
;
hsa-mir-1909-3p
;
hsa-mir-1915-5p
;
hsa-mir-1972
;
hsa-mir-197-5p
;
hsa-mir-298
;
hsa-mir-30b-3p
;
hsa-mir-3120-3p
;
hsa-mir-3132
;
hsa-mir-3154
;
hsa-mir-3165
;
hsa-mir-3179
;
hsa-mir-3605-5p
;
hsa-mir-3619-3p
;
hsa-mir-363-5p
;
hsa-mir-3652
;
hsa-mir-3671
;
hsa-mir-3688-5p
;
hsa-mir-3689a-3p
;
hsa-mir-3689b-3p
;
hsa-mir-3689c
;
hsa-mir-3690
;
hsa-mir-371a-5p
;
hsa-mir-371b-5p
;
hsa-mir-372-5p
;
hsa-mir-373-5p
;
hsa-mir-3919
;
hsa-mir-3940-3p
;
hsa-mir-4292
;
hsa-mir-4308
;
hsa-mir-4430
;
hsa-mir-4436b-3p
;
hsa-mir-4451
;
hsa-mir-4467
;
hsa-mir-4468
;
hsa-mir-4474-5p
;
hsa-mir-4505
;
hsa-mir-4532
;
hsa-mir-4632-5p
;
hsa-mir-4650-5p
;
hsa-mir-4651
;
hsa-mir-4685-5p
;
hsa-mir-4709-3p
;
hsa-mir-4711-5p
;
hsa-mir-4728-5p
;
hsa-mir-4739
;
hsa-mir-4756-5p
;
hsa-mir-4763-3p
;
hsa-mir-4764-5p
;
hsa-mir-4776-5p
;
hsa-mir-4804-5p
;
hsa-mir-502-5p
;
hsa-mir-5197-3p
;
hsa-mir-5586-3p
;
hsa-mir-5684
;
hsa-mir-5787
;
hsa-mir-6081
;
hsa-mir-616-5p
;
hsa-mir-6721-5p
;
hsa-mir-6722-3p
;
hsa-mir-6732-5p
;
hsa-mir-6735-5p
;
hsa-mir-6745
;
hsa-mir-6752-5p
;
hsa-mir-6753-5p
;
hsa-mir-6755-5p
;
hsa-mir-6756-5p
;
hsa-mir-6758-5p
;
hsa-mir-6766-5p
;
hsa-mir-6770-3p
;
hsa-mir-6770-5p
;
hsa-mir-6778-5p
;
hsa-mir-6779-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6785-5p
;
hsa-mir-6791-5p
;
hsa-mir-6799-5p
;
hsa-mir-6825-5p
;
hsa-mir-6837-5p
;
hsa-mir-6838-3p
;
hsa-mir-6841-3p
;
hsa-mir-6842-3p
;
hsa-mir-6842-5p
;
hsa-mir-6856-5p
;
hsa-mir-6873-5p
;
hsa-mir-6879-5p
;
hsa-mir-6880-5p
;
hsa-mir-6883-5p
;
hsa-mir-6894-5p
;
hsa-mir-7106-5p
;
hsa-mir-7110-5p
;
hsa-mir-7152-3p
;
hsa-mir-7843-5p
;
hsa-mir-8071
;
hsa-mir-922
Nearest miRNA
hsa-mir-103a-2/Upstream/110899; hsa-mir-1-1/Downstream/519656;
Nearest TSS
ENST00000382410/Upstream/31923;
ENST00000629058/Downstream/3368;
Nearest CpG islands
None/Target,
chr20-CpG: 39/Upstream/80090
,
chr20-CpG: 21/Downstream/4561
Nearest cancer related gene
BCL2L1
(OG, No orient, 0)
Upstream sequence
CCATTCATTAAAGGGTTTCCACCCTACAATTATGGCAGGAGAAGGGCTTTTGTGCTAGATCCTTTACTCGAGTCAAGCTATGGCAGCTGGCTATCATTAT
Downstream sequence
TCCATTTTACAGGCGGGAGAGACAGATGGACAAGACAGCCGAACAGGTTCAGCATTTCATCAGGTGACTCCAGGCAGGCAGTAATCTGGCTAAGGGTCTA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL219
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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