Basic Information
VIS ID
TVIS44006343
Fusion event
HTLV-1-CHSY3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
129492653/130156960 (Hg38)
End
129492653/130156960 (Hg38)
Orient
-
Location type
Intronic
Target gene
CHSY3
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-484
Nearest miRNA
hsa-mir-10397/Upstream/759813; hsa-mir-103a-1/Downstream/2060889;
Nearest TSS
ENST00000502646/Upstream/248873; ENST00000507584/Downstream/1005667;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/251041, chr5-CpG: 27/Downstream/838118
Upstream sequence
Ttttattgaatatctattctgtgtgaagactctcttagaatctacaaatatcattgttatggcagctgtaaggatatactgtcattcctaatttgtagat
Downstream sequence
taagaaactggggttaaattccttttctaaatcacttggctggtttgaggtgaggctttgattcaaacacaagtttacGAACTACTTACTTGTGGTCCCC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate