Basic Information
VIS ID
TVIS44006363
Fusion event
HTLV-1-ABRA integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
107808729/106796501 (Hg38)
End
107808729/106796501 (Hg38)
Orient
+
Location type
Intronic
Target gene
ABRA
miRNAs that regulate target gene
hsa-mir-628-5p
Nearest miRNA
hsa-mir-12123/Upstream/2312036; hsa-mir-10400/Downstream/5846992;
Nearest TSS
ENST00000518652/Upstream/26256; ENST00000520037/Downstream/499040;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/138138, chr8-CpG: 92/Downstream/1286126
Nearby gene
ABRA(-26257) ;
Upstream sequence
aaaaaaaaaaaaaaaaaaaaCCCATAAATGTGAAAAGAGACAATTAGATGTCAACTACATTGACTACCTTAGGATAAACGTGGAACAAAAATAAAACTAT
Downstream sequence
ATCCCTTATTGATAACGACCTTAGATAAAGTCCAGGGAGAGTTGACAagtataggggaagtggttaagagtatctgacctggagctgaaactactggttc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate