Basic Information
VIS ID
TVIS44006390
Fusion event
HTLV-1-LOC105371241 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
49125385/49091474 (Hg38)
End
49125385/49091474 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105371241
Nearest miRNA
hsa-mir-1225/Upstream/14927801; hsa-mir-11401/Downstream/1201142;
Nearest TSS
ENST00000527434/Upstream/451001; ENST00000565146/Downstream/68034;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/280121, chr16-CpG: 24/Downstream/183738
Nearby gene
CBLN1(-186444) ;
Upstream sequence
ACACACCAGAAAGGAAGGCAAACAGGCAGGAAAAGAGCAGAGTCTTTGCTATTGAAACCTATTTGTTTTCTCATTCCTTCTAGAAGAAACTTCATAATGT
Downstream sequence
CCTCTGCTCTTGAgtggagcagagaagagaagctttaagatcaaaaaaaccaagagtcagacttggaaactgccctctacaaacttagtgactcaataaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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