Basic Information
VIS ID
TVIS44006416
Fusion event
HTLV-1-MIR100HG integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
122242618/122371910 (Hg38)
End
122242618/122371910 (Hg38)
Orient
-
Location type
Intronic
Target gene
MIR100HG
Nearest miRNA
hsa-let-7a-2/Upstream/219602; hsa-mir-3167/Downstream/1009530;
Nearest TSS
ENST00000527297/Upstream/70147; ENST00000525711/Downstream/283765;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/919317, chr11-CpG: 113/Downstream/283660
Nearby gene
MIR100HG(-168848) ;
Nearest cancer related gene
MIR100HG(OG, No orient, 0)
Upstream sequence
aatctagaatggatagtacattgaggtggtacaaatgaggagtatcaatggcagcctctagaccggtcatagaggcaggattagtcccactaaccttcct
Downstream sequence
catgtaataagactttctaggaaaagaaacttatcagaatgcgggaggagGTCTTCTTAGAAGGAGTAAGCTTAGTACACAAGCAAGCAGTGCAAATGGC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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