Basic Information
VIS ID
TVIS44006424
Fusion event
HTLV-1-C16orf97 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
52076936/52043024 (Hg38)
End
52076936/52043024 (Hg38)
Orient
+
Location type
Intronic
Target gene
C16orf97
Nearest miRNA
hsa-mir-1225/Upstream/1300647; hsa-mir-11401/Downstream/4202496;
Nearest TSS
ENST00000527434/Upstream/271460; ENST00000568711/Downstream/35598;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/886675, chr16-CpG: 125/Downstream/502700
Upstream sequence
tgttcactccttctatacctaaattattgggagtttttacatatgtaggttgaaccatccttgtatcccaggaatagatcaaggaatagattccacttga
Downstream sequence
tcatggactgtgatccttttaatatgctgttgaatatggtttgctactattttgattaagatattttgcatctatgctcatcagggatattggcctataa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate