Basic Information
VIS ID
TVIS44006427
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
10284902/10284905 (Hg38)
End
10284902/10284905 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-3976/Upstream/3910480; hsa-mir-1-2/Downstream/474679;
Nearest TSS
ENST00000575820/Upstream/159565; ENST00000580258/Downstream/87475;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/152767, chr18-CpG: 19/Downstream/129452
Nearby gene
LINC01254(No orient, 120228)
Upstream sequence
AATAAAACTCGGAATGCATGTTCAGGAAAGCAGGAAGCTTTGAAGTTGAAAAAGCCAAACAGGAACAGCTGTCGTGATTGGTGCGGTGCACATTCGGCCT
Downstream sequence
GACGTGACAGACCTGTCCCATGCACTGTCCCTGTGCCTGAGGGACAGCTGGGGAGCAGCAAGGAGCCTTTCCTTTCATGGGGATTTCTGCTGGTGTCCCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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