Basic Information
VIS ID
TVIS44006431
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
16175582/16035460 (Hg38)
End
16175582/16035460 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-3125/Upstream/3298016; hsa-mir-10b/Downstream/3312969;
Nearest TSS
ENST00000437798/Upstream/93211; ENST00000442387/Downstream/14967;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/21163, chr2-CpG: 50/Downstream/472635
Nearby gene
GACAT3(No orient, 14967)
Upstream sequence
gggaggctgaggagagcggatcgaagagttcaagaccagcccgggcaacatggtgaaaccctgtgtctacaaaaaatacaaaaattagtcgggtgtggtg
Downstream sequence
atgtgcatttgtagtcccagctactcgagaggctaaggtgggaggatcgcttgagcccaggaggcagaggctgcagtgagctgtaattgtgtcactgcac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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