Basic Information
VIS ID
TVIS44006458
Fusion event
HTLV-1-RPL32P31 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
78518236/80544436 (Hg38)
End
78518236/80544436 (Hg38)
Orient
+
Location type
Intronic
Target gene
RPL32P31
Nearest miRNA
hsa-mir-10226/Upstream/124943; hsa-mir-1250/Downstream/580840;
Nearest TSS
ENST00000595228/Upstream/66593; ENST00000573746/Downstream/383;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/65453, chr17-CpG: 27/Downstream/514
Nearby gene
RPTOR(+389) ;
Upstream sequence
cttcggcctcccaaagtgctgggattacaggcgtgagccacggcgcccggccTTTCACTTGGTTCTCTATGAAAAAATTAAAGAGAAAATCTGATTGACA
Downstream sequence
CTGTGGAGGACACTACACTCCAAAAAAAAAAGTACTATATTTTCTAATATTATCAGTGCTTTTTAATATTTTCTAATATTATCAGTGAAGCTTTTGCCGC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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