Basic Information
VIS ID
TVIS44006462
Fusion event
HTLV-1-LOC105373481 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p25.3
Reference genome
GRCh37/hg19
Start
908183/912497 (Hg38)
End
908183/912497 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105373481
Nearest miRNA
hsa-mir-10b/Downstream/5062165;
Nearest TSS
ENST00000437798/Upstream/7046; ENST00000452177/Downstream/8627;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/43092, chr2-CpG: 151/Downstream/37503
Upstream sequence
TGAAGTGGAAGGACCTTACTATTCATCTGTGTGAAGGGGAAGGACCTTAGTATTCATGTATGTGAGGTGGAAGGACCTTAGTATTCATGTATATGAAGGG
Downstream sequence
GAAGGAGCTTAGTCTTCATGTATGTGAGGTGGAAGGACCTTAGTCTTCATGTATGTGAGGTGAAAGGACCTTAGTCTTCATGTATGTGAGGTGGAAGGAC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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