Basic Information
VIS ID
TVIS44006503
Fusion event
HTLV-1-CXADRP3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
14498589/14498590 (Hg38)
End
14498589/14498590 (Hg38)
Orient
-
Location type
ncRNA_splicing
Target gene
CXADRP3
Nearest miRNA
hsa-mir-3976/Upstream/887390; hsa-mir-1-2/Downstream/331576;
Nearest TSS
ENST00000575820/Upstream/366100; ENST00000579292/Downstream/44556;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/11104, chr18-CpG: 59/Downstream/248927
Upstream sequence
tcccttgagagtttctcatgctgtgtagaagaagctctttagtttaattaaatcatacttgtcaattttcatttttctggcaattgcttttgaggactta
Downstream sequence
cccataaattcattgccaagtgcaatgtccagatgaatatttcctaggttttcttccaggatttttatagGCAGAGGATGTAATCTCATGTCAATGGGTC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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