Basic Information
VIS ID
TVIS44006508
Fusion event
HTLV-1-LOC107985998 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q37.1
Reference genome
GRCh37/hg19
Start
232346826/231482115 (Hg38)
End
232346826/231482115 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC107985998
Nearest miRNA
hsa-mir-10b/Upstream/119322; hsa-mir-1244-1/Downstream/231199;
Nearest TSS
ENST00000437798/Upstream/17521; ENST00000313965/Downstream/1526;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/16677, chr2-CpG: 41/Downstream/1557
Nearby gene
NCL(-17621) ;
Upstream sequence
tcatggtggcagaatgTCTCTTGCTGTGGTTCAAGCAATGAATCTCATCTCTACACATCTTAGAGTCCAGAGGGAGCTAGAAAACATCTTTCCCAGAAGC
Downstream sequence
CATCTCCCACAAAGGAGTACCCCAGACTGTCCCTGGATTACAGCCTCACCCCTGTGCCCAGGCAAGGTAGTAGTTATGGTAATGTCAGTGTGATCCTGGG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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