VISDB Viral Integration Site DataBase

VIS ID

TVIS44006514

Fusion event

HTLV-1-chr4 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr4

Cytoband

p15.2

Reference genome

Start

End

26190402/26188780 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

LOC105374545 ; RBPJ

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-155-5p ; hsa-mir-124-3p ; hsa-mir-18a-5p ; hsa-let-7b-5p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-32-3p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-545-3p ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-3064-3p ; hsa-mir-6838-5p ; hsa-mir-6077 ; hsa-mir-4468 ; hsa-mir-193b-5p ; hsa-mir-561-3p ; hsa-mir-619-3p ; hsa-mir-4774-5p ; hsa-mir-5585-3p ; hsa-mir-6765-3p ; hsa-mir-490-3p ; hsa-mir-548d-3p ; hsa-mir-548h-3p ; hsa-mir-548z ; hsa-mir-548ac ; hsa-mir-548bb-3p ; hsa-mir-218-5p ; hsa-mir-8061 ; hsa-mir-4760-5p ; hsa-mir-4715-3p ; hsa-mir-532-5p ; hsa-mir-3923 ; hsa-mir-302f ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-7-5p ; hsa-mir-4446-5p ; hsa-mir-6814-5p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-133a-3p ; hsa-mir-153-5p ; hsa-mir-1910-3p ; hsa-mir-208a-5p ; hsa-mir-208b-5p ; hsa-mir-2467-3p ; hsa-mir-25-3p ; hsa-mir-3140-3p ; hsa-mir-320a ; hsa-mir-320b ; hsa-mir-320c ; hsa-mir-320d ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-3680-3p ; hsa-mir-3714 ; hsa-mir-4429 ; hsa-mir-450b-5p ; hsa-mir-4708-3p ; hsa-mir-4742-5p ; hsa-mir-507 ; hsa-mir-557 ; hsa-mir-6511a-5p ; hsa-mir-6511b-5p ; hsa-mir-6809-5p ; hsa-mir-6811-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-9-3p ; hsa-mir-2681-5p ; hsa-mir-4318 ; hsa-mir-4474-3p ; hsa-mir-4693-5p ; hsa-mir-6815-3p ; hsa-mir-892a

Nearest miRNA

hsa-mir-12113/Upstream/1668490; hsa-mir-1243/Downstream/2630802;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/159710, chr4-CpG: 20/Downstream/130367

Nearby gene

RBPJ(+130930) ;

Upstream sequence

taattttcaaatcagtcagccaaattagatatattccttgtcattaaaagtgtgactttattgttcaatttaagtaagtgtcttaatattcattttgaag

Downstream sequence

aatattataaaaaccactgaggaataaattatgcatgcatcatataagatagattactaaagagcaatcaagtttacattgatatagatctgatttaatt