Basic Information
VIS ID
TVIS44006535
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.13
Reference genome
GRCh37/hg19
Start
18259984/17933490 (Hg38)
End
18259984/17933490 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/655515; hsa-mir-101-1/Downstream/949712;
Nearest TSS
ENST00000473358/Upstream/110508; ENST00000641892/Downstream/82222;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/107143, chr1-CpG: 70/Downstream/174121
Nearby gene
ACTL8(+106426) ;
Upstream sequence
aaaagttttttcttgtttagaaatcactttggggttcgaaaaatatggatccattggagaacgtggtgaagcttgtcatggcgagttttcagtgaattaa
Downstream sequence
aggagccggaatttaatgtcattctggccgcgtcatttcttccccaaggagggcaatatacgaggtcagaccagctccCTACACTGGGAACGTGCACTTG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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