Basic Information
VIS ID
TVIS44006539
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.2
Reference genome
GRCh37/hg19
Start
69473448/69007765 (Hg38)
End
69473448/69007765 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1C ; FRA1L
Nearest miRNA
hsa-mir-101-1/Upstream/824155; hsa-mir-11399/Downstream/2059866;
Nearest TSS
ENST00000473358/Upstream/33755; ENST00000425517/Downstream/48133;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/510442, chr1-CpG: 131/Downstream/559519
Nearby gene
DEPDC1-AS1(No orient, 469138)
Upstream sequence
gattacaggcacgtgccacaatgcccagctaatttttgtattttcagtagagaccgggtttcaccatgttggcctggatggtcttgatctcctgacctca
Downstream sequence
tgatctgcctgtcttggcctcccaaagtgctgggattacaggtgtgaaccaccgtgcccaaccACAGATCATACTCTTAAAGAGAGAAGGTATGATTGCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate