Basic Information
VIS ID
TVIS44006557
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
32481950/32193022 (Hg38)
End
32481950/32193022 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1265/Upstream/1824357; hsa-mir-107/Downstream/2886576;
Nearest TSS
ENST00000439456/Upstream/136591; ENST00000628416/Downstream/73267;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/82854, chr10-CpG: 164/Downstream/153267
Nearby gene
EPC1(-74694) ;
Upstream sequence
gtgaataatggtgctatgaatataggtatacaaatatctctccaaggccctacttttgattattttgggtgtatactcagaaagaaaactgccagataat
Downstream sequence
gtggtagttctattttcaattttttgaggagccgtcatgcgattttccacagtggccgcaccactttacatttttaccagcagtgtaggagggttccaca
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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