Basic Information
VIS ID
TVIS44006575
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
59682249/59914776 (Hg38)
End
59682249/59914776 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-129-2/Upstream/319618; hsa-let-7a-2/Downstream/294295;
Nearest TSS
ENST00000527297/Upstream/35967; ENST00000644529/Downstream/23656;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/16392, chr11-CpG: 21/Downstream/600534
Nearby gene
OOSP1(No orient, 28103)
Upstream sequence
aaagttctgtggcttctaccactactaacttgtgacaggctgctgtatttctcagataattgcagctgttgcctaactggtattttttccttggtccttg
Downstream sequence
agaatctattaaatattctcaagacagcagccagagccattctgttaatacccagtgtatttattttccaaatctgctgtaacaaagcaccacaaattgg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate