Basic Information
VIS ID
TVIS44006583
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
34715696/34562761 (Hg38)
End
34715696/34562761 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1244-3/Upstream/8688682; hsa-let-7i/Downstream/7760939;
Nearest TSS
ENST00000382841/Upstream/343908; ENST00000553138/Downstream/3753817;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/212082, chr12-CpG: 44/Downstream/3575465
Upstream sequence
cagaatggacaaagaaagtgttcccaaactgttgaatccaatgaaaggtttagctctgagatgaatgcacacaacacaaagcagtttcacaaaaacttct
Downstream sequence
ttctagtttgcatatgaagatatttcctttttcaacataagactcaatgaactcccaaataccccttcgcagattctataaaaaccgtgtttccaaacta
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate