Basic Information
VIS ID
TVIS44006589
Fusion event
HTLV-1-LOC105370214 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
57229161/56655027 (Hg38)
End
57229161/56655027 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA13B
Target gene
LOC105370214
Nearest miRNA
hsa-mir-1297/Upstream/1480479; hsa-mir-1267/Downstream/4544771;
Nearest TSS
ENST00000623511/Upstream/1071503; ENST00000377931/Downstream/485891;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/3452817, chr13-CpG: 25/Downstream/485810
Nearby gene
PRR20D(+485891) ;
Upstream sequence
tccatatgtgatagaaattggcttaaaattttcttttaatattattctcaaatgttattgtatcatagtcatTTTTATCTTTGTTTTTCAAATTCTAGGA
Downstream sequence
CACTATTAAATTGTGTAATTTTCAAATAATTTCTCAAAGCAATATATTTATGTCTGTAACTGACAAGTTCTTAGGTgaaggtataatactcatataactg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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