Basic Information
VIS ID
TVIS44006600
Fusion event
HTLV-1-BAZ1A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
35335256/34866050 (Hg38)
End
35335256/34866050 (Hg38)
Orient
+
Location type
Intronic
Target gene
BAZ1A
miRNAs that regulate target gene
hsa-mir-373-3p ; hsa-mir-375 ; hsa-mir-98-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-208a/Upstream/3851308; hsa-mir-1185-1/Downstream/2086259;
Nearest TSS
ENST00000550708/Upstream/3739; ENST00000557373/Downstream/8293;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/151060, chr14-CpG: 189/Downstream/7589
Upstream sequence
gctgaggcaggaggatcacttgaagccaggagttcgagaccagactgcgcaacaaagcgagaccctgtctccaccaaaaattgaagaaaaaaattagcca
Downstream sequence
gggggcgcacatctatagtccttgctactcaggaggctgaggtgggaagagcacctgaacccaggagttcaaggctgcagtgagctataattacaccact
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate