Basic Information
VIS ID
TVIS44006609
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
99743740/99277403 (Hg38)
End
99743740/99277403 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1260a/Upstream/4139417; hsa-mir-1185-1/Downstream/832016;
Nearest TSS
ENST00000550708/Upstream/5879; ENST00000553636/Downstream/54612;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/2299, chr14-CpG: 20/Downstream/43090
Nearby gene
BCL11B(-5690) ;
Nearest cancer related gene
BCL11B(OG, -5690) ;
Upstream sequence
GTGTAACTGAAACTGCAAGGAAGACCGTTTTCCTGAAGATGCTGAGAGCTCTGTTTTGAAGACACACACATATCCGTGAGTTTGAATTCAGTGGTCTATT
Downstream sequence
GACCATCCATCTGCCCTTTGTAGAGAACAGACAAGGAAAATAAAGAGAGTTAAAGTGGTTCAAATGAGGGACTCAGAAAGGAATTTTCAGTTCCGACTCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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