Basic Information
VIS ID
TVIS44006654
Fusion event
HTLV-1-SCHLAP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
181754194/180889467 (Hg38)
End
181754194/180889467 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA2G
Target gene
SCHLAP1
Nearest miRNA
hsa-mir-10b/Upstream/1028559; hsa-mir-1244-1/Downstream/416126;
Nearest TSS
ENST00000437798/Upstream/197013; ENST00000602632/Downstream/77781;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/882320, chr2-CpG: 161/Downstream/90597
Upstream sequence
aacacatcaaaacaaagaaaattaaacatcaatatccatcatgaatgtgggcacaaaaatactcaaaagtattagaaaattgaatccagtgatatataag
Downstream sequence
aaaataatgacttatattaaaaagtaatatttacactgggaatgtaagatttgttcaaaattgaacaaattattcaattaacaatacagaagaaaagtca
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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