Basic Information
VIS ID
TVIS44006665
Fusion event
HTLV-1-LOC102724355 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
28618857/27246538 (Hg38)
End
28618857/27246538 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC102724355
Nearest miRNA
hsa-let-7c/Upstream/292495; hsa-mir-3197/Downstream/3128756;
Nearest TSS
ENST00000624081/Upstream/280025; ENST00000447384/Downstream/114626;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/102551, chr21-CpG: 29/Downstream/1638565
Nearby gene
MIR5009(No orient, 40965)
Upstream sequence
aagtgctcctccatttaaatttgaattctgactcagccatgtcctaactatgtgaccactataaaagtcattttgtctctctgtaaaatgtggatggtga
Downstream sequence
tgactaggttgttacaaaggtaaatgagttagtaaatatttagtgcttagaacagtgtctagccttcaggaagtgctcaacaaatgttagtGTTTTTTAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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