Basic Information
VIS ID
TVIS44006668
Fusion event
HTLV-1-LOC105372790 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.11
Reference genome
GRCh37/hg19
Start
35371202/33998901 (Hg38)
End
35371202/33998901 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105372790
Nearest miRNA
hsa-let-7c/Upstream/448173; hsa-mir-3197/Downstream/1721814;
Nearest TSS
ENST00000624081/Upstream/29382; ENST00000381151/Downstream/74323;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/82997, chr21-CpG: 151/Downstream/73886
Upstream sequence
AAGATGGTCGTACCTGAAGCCTAAGCCGAGGCCTGAGCGGCACCCTCAAGAGTCCCCTCTTGTCTCCTCAGCTGGAATAACTTTTTCTCAACTGGTGGCT
Downstream sequence
ATCTTGGACGTTAGTTTAAAGCTCTGTTGTAATGTATGTCACCCTGACTGGAGTTCTAGGTATTTTGTTTCTTTTCTAGATTGAGATCTTTGGGGCAACC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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