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TVIS44006712
Basic Information
VIS ID
TVIS44006712
Fusion event
HTLV-1-F2RL1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
76128973/76833148 (Hg38)
End
76128973/76833148 (Hg38)
Orient
+
Location type
Exonic
Target gene
F2RL1
miRNAs that regulate target gene
hsa-mir-1-3p
;
hsa-mir-190a-3p
;
hsa-mir-410-3p
;
hsa-mir-511-3p
;
hsa-mir-1277-5p
;
hsa-mir-4495
;
hsa-mir-5011-5p
;
hsa-mir-223-5p
;
hsa-mir-205-3p
;
hsa-mir-640
;
hsa-mir-6821-3p
;
hsa-mir-6790-3p
;
hsa-mir-1224-3p
;
hsa-mir-6813-3p
;
hsa-mir-744-3p
;
hsa-mir-4423-5p
;
hsa-mir-6501-5p
;
hsa-mir-4430
;
hsa-mir-3652
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-3135b
;
hsa-mir-367-5p
;
hsa-mir-1266-3p
;
hsa-mir-454-3p
;
hsa-mir-4295
;
hsa-mir-3666
;
hsa-mir-301b-3p
;
hsa-mir-301a-3p
;
hsa-mir-130b-3p
;
hsa-mir-130a-3p
;
hsa-mir-5089-5p
;
hsa-mir-6878-3p
;
hsa-mir-466
;
hsa-mir-4672
;
hsa-mir-3941
;
hsa-mir-6744-3p
;
hsa-mir-4757-5p
;
hsa-mir-5589-5p
;
hsa-mir-4731-5p
;
hsa-mir-6778-3p
;
hsa-mir-6506-5p
;
hsa-mir-619-5p
;
hsa-mir-150-5p
;
hsa-mir-212-5p
;
hsa-mir-186-3p
;
hsa-mir-520h
;
hsa-mir-520g-3p
;
hsa-mir-512-3p
;
hsa-mir-603
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-8485
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-6833-3p
;
hsa-mir-4768-5p
;
hsa-mir-6894-3p
;
hsa-mir-6514-3p
;
hsa-mir-6873-3p
;
hsa-mir-5581-5p
;
hsa-mir-4297
;
hsa-mir-4763-5p
;
hsa-mir-942-5p
;
hsa-mir-1304-3p
;
hsa-mir-6747-3p
;
hsa-mir-483-3p
Nearest miRNA
hsa-mir-10397/Upstream/3954485; hsa-mir-103a-1/Downstream/6007007;
Nearest TSS
ENST00000502646/Upstream/14171;
ENST00000513010/Downstream/16853;
Nearest CpG islands
None/Target,
chr5-CpG: 87/Upstream/12884
,
chr5-CpG: 104/Downstream/120462
Upstream sequence
TGTAATGTGCTTATTGGCTTTTTCTATGGCAACATGTACTGTTCCATTCTCTTCATGACCTGCCTCAGTGTGCAGAGGTATTGGGTCATCGTGAACCCCA
Downstream sequence
TGGGGCACTCCAGGAAGAAGGCAAACATTGCCATTGGCATCTCCCTGGCAATATGGCTGCTGATTCTGCTGGTCACCATTCCTTTGTATGTCGTGAAGCA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL111
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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