Basic Information
VIS ID
TVIS44006724
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q27
Reference genome
GRCh37/hg19
Start
164602354/164181322 (Hg38)
End
164602354/164181322 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA6E
Nearest miRNA
hsa-mir-10398/Upstream/5416569; hsa-mir-1913/Downstream/2328032;
Nearest TSS
ENST00000381078/Upstream/71628; ENST00000456118/Downstream/167322;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/208530, chr6-CpG: 28/Downstream/155690
Nearby gene
QKI(+602726) ;
Upstream sequence
CAAAGCCAACAAATTCTGGTGGCAAGtataaacctaaaataaaattctaaggtcccccaaccttctgaatagaccctttgtcttggccaaaggcattcca
Downstream sequence
gggttaacctgaaaatctagttgaggccatggtggaagaggaggttggacagacttcattatatcctacagcattagcatcaacacagaccttcagtctg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate