Basic Information
VIS ID
TVIS44006727
Fusion event
HTLV-1-LOC100506098 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
20261137/20221514 (Hg38)
End
20261137/20221514 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC100506098
Nearest miRNA
hsa-mir-1302-6/Upstream/516078; hsa-mir-10399/Downstream/1249544;
Nearest TSS
ENST00000635602/Upstream/4110; ENST00000453564/Downstream/75194;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/512276, chr7-CpG: 138/Downstream/108866
Nearby gene
MACC1(-4124) ;
Upstream sequence
TAACAACAGAGAGAGCTCTGTGCAGTTTTCACTGGAATGCCTGTGGATTGCTTGTGTCATAACTGTAATCTAAAGAGTTGTCCATTTGTTGATTCCTTTG
Downstream sequence
TATTTGTATTGGTAGAATTGCCACTATCAAACCAAGATCTTTAGCTGCCTTTGTATCAACTTCTTTGGAGCTTATGTGATTTTCCAGAAAATTTCCAAGG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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