Basic Information
VIS ID
TVIS44006811
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
182809618/181944891 (Hg38)
End
182809618/181944891 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2G
Nearest miRNA
hsa-mir-10b/Upstream/639239; hsa-mir-1244-1/Downstream/2434084;
Nearest TSS
ENST00000437798/Upstream/24285; ENST00000461410/Downstream/9350;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/52099, chr2-CpG: 53/Downstream/771075
Nearby gene
PPP1R1C(+9350) ;
Upstream sequence
gagccccctatacgctatgctttttcctatacttagataactatgttaaagtttagtttacaaattaggtaagtaagaggttaacaatgataactaataa
Downstream sequence
taaaatagaacaattgtaccaatatactacaataaaagttatgtgaataggatctctctcccaaatatcttactgtactcaacattcttgtgatgacgtg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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