Basic Information
VIS ID
TVIS44006815
Fusion event
HTLV-1-chr20 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
11173907/11193259 (Hg38)
End
11173907/11193259 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA20B
Nearest miRNA
hsa-mir-103a-2/Upstream/543564; hsa-mir-1-1/Downstream/7277356;
Nearest TSS
ENST00000382410/Upstream/165499; ENST00000450368/Downstream/75576;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/518296, chr20-CpG: 37/Downstream/493615
Nearby gene
LOC339593(-73400) ;
Upstream sequence
GCTACACCAGTTGTCAGCGTTGACTATATATTTTCTACatattttataattaataataataattCTTTTTGGGAAGGTTTAGCCAATAGAAGGGAGATGG
Downstream sequence
GGTGGTGGTTAAGTACCTCAGGATTGCAACTTGAGAGTGAATGGCAAGGAAACCACTTAATCTTTAAAacacacacacacacacacacacacTGTATTTC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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