Basic Information
VIS ID
TVIS44006846
Fusion event
HTLV-1-LOC102724520 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
15683705/15683474 (Hg38)
End
15683705/15683474 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC102724520
Nearest miRNA
hsa-mir-3691/Upstream/5243680; hsa-mir-10398/Downstream/458082;
Nearest TSS
ENST00000381078/Upstream/20416; ENST00000451285/Downstream/311470;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/20293, chr6-CpG: 107/Downstream/445287
Nearby gene
DTNBP1(-20416) ;
Upstream sequence
agtgccacaaatccagcatcgtgatagaggatgagcaagacacagcctctgctccagggagctcagagtctggtgatgggttggacaagcaaaAGAGTGT
Downstream sequence
TACTGAATAAGGCGCCGTTATATTTATTTGCTGAACATCCAATGAATATTTAACAAGTACCTTTGATGTGTCAGTAACACACAagcacacagggcagggg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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