Basic Information
VIS ID
TVIS44006875
Fusion event
HTLV-1-SLC44A3-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
95194243/94728687 (Hg38)
End
95194243/94728687 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA1M
Target gene
SLC44A3-AS1
Nearest miRNA
hsa-mir-101-1/Upstream/184908; hsa-mir-11399/Downstream/3316555;
Nearest TSS
ENST00000473358/Upstream/136390; ENST00000422520/Downstream/91655;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/186604, chr1-CpG: 70/Downstream/91359
Upstream sequence
CAAAGACAATAATCATTGATACTGGGCAGTGTTTCTTTGGTTTTAGCCTTGAAGGAAAGAATCAGATAACAAGCATTTATGTGGCTATCTGGTTACttct
Downstream sequence
tcttcttgtttttttttttttttgagacggagtttcactcttgtcacccaggctagagtgcaatggcgtgatcttggctcaccgcaacctccacctcccg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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