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TVIS44006881
Basic Information
VIS ID
TVIS44006881
Fusion event
HTLV-1-DARS2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
173794950/173825812 (Hg38)
End
173794950/173825812 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1G
Target gene
DARS2
miRNAs that regulate target gene
hsa-mir-30a-5p
;
hsa-mir-186-5p
;
hsa-mir-222-3p
;
hsa-mir-24-3p
;
hsa-mir-7151-3p
;
hsa-mir-5095
;
hsa-mir-6508-3p
;
hsa-mir-4726-5p
;
hsa-mir-4640-5p
;
hsa-mir-661
;
hsa-mir-6853-5p
;
hsa-mir-3116
;
hsa-mir-1254
;
hsa-mir-664a-5p
;
hsa-mir-4794
;
hsa-mir-6872-3p
;
hsa-mir-6504-3p
;
hsa-mir-4438
;
hsa-mir-6869-5p
;
hsa-mir-4279
;
hsa-mir-1200
;
hsa-mir-365b-5p
;
hsa-mir-365a-5p
;
hsa-mir-8052
;
hsa-mir-3199
;
hsa-mir-6829-3p
;
hsa-mir-6791-3p
;
hsa-mir-1976
;
hsa-mir-3653-5p
;
hsa-mir-6747-3p
;
hsa-mir-6727-3p
;
hsa-mir-4722-3p
;
hsa-mir-544b
;
hsa-mir-4324
;
hsa-mir-660-3p
;
hsa-mir-455-5p
;
hsa-mir-8062
;
hsa-mir-552-3p
;
hsa-mir-7977
;
hsa-mir-20b-3p
;
hsa-mir-4539
;
hsa-mir-146a-3p
;
hsa-mir-5690
;
hsa-mir-2114-5p
;
hsa-mir-5588-3p
;
hsa-mir-3664-5p
;
hsa-mir-514a-5p
;
hsa-mir-4714-5p
;
hsa-mir-6732-3p
;
hsa-mir-504-5p
;
hsa-mir-4322
;
hsa-mir-4296
;
hsa-mir-4265
;
hsa-mir-4417
;
hsa-mir-2861
;
hsa-mir-6735-3p
;
hsa-mir-640
;
hsa-mir-4713-5p
;
hsa-mir-2116-3p
;
hsa-mir-532-3p
;
hsa-mir-8079
;
hsa-mir-1245a
;
hsa-mir-1273e
;
hsa-mir-4266
;
hsa-mir-4722-5p
;
hsa-mir-6134
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-6840-3p
;
hsa-mir-4459
;
hsa-mir-4768-3p
;
hsa-mir-6500-3p
;
hsa-mir-3614-5p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-4779
;
hsa-mir-4695-5p
;
hsa-mir-34b-3p
;
hsa-mir-4284
;
hsa-mir-8057
Nearest miRNA
hsa-mir-101-1/Upstream/1681168; hsa-mir-1182/Downstream/2142558;
Nearest TSS
ENST00000473358/Upstream/1092;
ENST00000460076/Downstream/15101;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/855
,
chr1-CpG: 63/Downstream/42222
Upstream sequence
cccgcctccgcctcccatagtgctgggattacaggcgtgagccaccgcgcccggcTTTTCCCCTGTTCTTAACTGGATAGCCTTATGTGTAGAAGCGAAA
Downstream sequence
TTCACTCTCATTATATTCATTATACGGCAGTTTTTTTTCCCTGAGTTTTTAGAAAGACCACAAAAAGGTAACCACGTAATATATAGAATACTCTGCTTTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL12
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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