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Viral Integration Site DataBase
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TVIS44006893
Basic Information
VIS ID
TVIS44006893
Fusion event
HTLV-1-ARID5B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
63752675/61992916 (Hg38)
End
63752675/61992916 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10C
Target gene
ARID5B
miRNAs that regulate target gene
hsa-mir-128-3p
;
hsa-mir-101-3p
;
hsa-mir-22-3p
;
hsa-mir-196a-5p
;
hsa-mir-196b-5p
;
hsa-mir-1277-5p
;
hsa-mir-3653-3p
;
hsa-mir-3658
;
hsa-mir-5011-5p
;
hsa-mir-186-3p
;
hsa-mir-320a
;
hsa-mir-373-5p
;
hsa-mir-576-3p
;
hsa-mir-616-5p
;
hsa-mir-767-3p
;
hsa-mir-320b
;
hsa-mir-320c
;
hsa-mir-320d
;
hsa-mir-4426
;
hsa-mir-4429
;
hsa-mir-4491
;
hsa-mir-4647
;
hsa-mir-4657
;
hsa-mir-4662b
;
hsa-mir-371b-5p
;
hsa-mir-6833-5p
;
hsa-mir-570-5p
;
hsa-mir-3692-3p
;
hsa-mir-548ag
;
hsa-mir-548ai
;
hsa-mir-4476
;
hsa-mir-4694-3p
;
hsa-mir-5692a
;
hsa-mir-6876-5p
;
hsa-mir-548ba
;
hsa-mir-33a-5p
;
hsa-mir-185-5p
;
hsa-mir-432-5p
;
hsa-mir-33b-5p
;
hsa-mir-1284
;
hsa-mir-4306
;
hsa-mir-4644
;
hsa-mir-5192
;
hsa-mir-6813-3p
;
hsa-mir-583
;
hsa-mir-573
;
hsa-mir-3156-5p
;
hsa-mir-3616-5p
;
hsa-mir-4670-3p
;
hsa-mir-190a-3p
;
hsa-mir-656-3p
;
hsa-mir-4795-3p
;
hsa-mir-524-5p
;
hsa-mir-520d-5p
;
hsa-mir-3190-3p
;
hsa-mir-7856-5p
;
hsa-mir-552-3p
;
hsa-mir-127-5p
;
hsa-mir-7843-3p
;
hsa-mir-140-3p
;
hsa-mir-4482-3p
;
hsa-mir-152-5p
;
hsa-mir-597-3p
;
hsa-mir-182-3p
;
hsa-mir-4680-5p
;
hsa-mir-126-5p
;
hsa-mir-218-2-3p
;
hsa-mir-3928-3p
;
hsa-mir-620
;
hsa-mir-1270
;
hsa-mir-4531
;
hsa-mir-324-5p
;
hsa-mir-423-5p
;
hsa-mir-3184-5p
;
hsa-mir-6866-3p
;
hsa-mir-188-5p
;
hsa-mir-6743-5p
;
hsa-mir-4688
Nearest miRNA
hsa-mir-1265/Upstream/4688357; hsa-mir-107/Downstream/1380041;
Nearest TSS
ENST00000439456/Upstream/91232;
ENST00000647323/Downstream/53746;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/89376
,
chr10-CpG: 67/Downstream/275366
Upstream sequence
ATCTCAGGGCTGCCCCACTTGCTTACTGTGTCGAGAATTACAAAATCATTAAGGGTGGGGCAGCACCAGCTGACTTACAGTACAAACCATTTCTCAAAAT
Downstream sequence
AACCACAACAGTGCAATACTGATGTGTAATTTACGTCACAGTTTGTTTTTATGAAATAGTTTGTGGCATTTTCATTTCTATTCCGGATGGAATCTTGTTC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL12
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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