Basic Information
VIS ID
TVIS44006895
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.4
Reference genome
GRCh37/hg19
Start
6850903/6829672 (Hg38)
End
6850903/6829672 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-210/Upstream/2973531; hsa-let-7a-2/Downstream/405094;
Nearest TSS
ENST00000527297/Upstream/29983; ENST00000299454/Downstream/15980;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/145960, chr11-CpG: 58/Downstream/96617
Nearby gene
OR10A5(+16011) ;
Upstream sequence
ggcagggtttcaccatgttggccaggatgatctcaaactcctgacctcaggtgattcacccgccttggcctcccaaagtgctgggattacaggcatgagc
Downstream sequence
caAGTCTCCTaatcctggtaattcttcattggaaaaattcttactcaaactttggttcaattcccattttcactgctactgccatgagcctagccaagcc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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