Basic Information
VIS ID
TVIS44006954
Fusion event
HTLV-1-ARSG integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
66390683/68394542 (Hg38)
End
66390683/68394542 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARSG
miRNAs that regulate target gene
hsa-mir-218-5p
Nearest miRNA
hsa-mir-10226/Upstream/922957; hsa-mir-1250/Downstream/29909;
Nearest TSS
ENST00000595228/Upstream/47397; ENST00000590690/Downstream/5614;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/102151, chr17-CpG: 70/Downstream/62666
Upstream sequence
aaataaataaataaataaataaaaatcaataaaacaacaaagaaatcttgtaggtgtggtggtacatgcttgtagtcccagctactcttggagtcagacg
Downstream sequence
agtattacttcagcccaggagttcaaggttacagtgagttatgatcacacactgcactccagcctggatgacagagcaagactctgtctctaaaaaaatt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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