Basic Information
VIS ID
TVIS44006971
Fusion event
HTLV-1-LINC01805 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p14
Reference genome
GRCh37/hg19
Start
64721373/64494239 (Hg38)
End
64721373/64494239 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LINC01805
Nearest miRNA
hsa-mir-1301/Upstream/153391; hsa-mir-10b/Downstream/31274;
Nearest TSS
ENST00000437798/Upstream/7886; ENST00000487769/Downstream/29854;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/39164, chr2-CpG: 77/Downstream/29768
Nearby gene
AFTPH(+30066) ;
Upstream sequence
TCTATATCTATTCTCAGCCAGAGCCACCTGGTTATATGCATATAATGTGATATCACTGAGAAATTTTCGGAGAGCTGAGCTTCCCAGACAGGTGGCTGAT
Downstream sequence
TACCTAAGCAATCTATAGTAATTATATACatggcacagacgttaagtgtgtgagctctagaatcagacagccactatctaaattgcgactctaccgttgc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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