VISDB Viral Integration Site DataBase

VIS ID

TVIS44006979

Fusion event

HTLV-1-HDLBP integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

q37.3

Reference genome

Start

End

242186124/241246709 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-34a-5p ; hsa-mir-7-5p ; hsa-mir-1301-3p ; hsa-mir-877-3p ; hsa-mir-548d-5p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-423-3p ; hsa-mir-365a-3p ; hsa-mir-222-3p ; hsa-mir-6757-5p ; hsa-mir-4753-5p ; hsa-mir-506-3p ; hsa-mir-548at-5p ; hsa-mir-124-3p ; hsa-mir-7150 ; hsa-mir-6739-5p ; hsa-mir-6799-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-4668-5p ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-6851-5p ; hsa-mir-6797-5p ; hsa-mir-3689d ; hsa-mir-1249-5p ; hsa-mir-6077 ; hsa-mir-4722-5p ; hsa-mir-6134 ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-6868-5p ; hsa-mir-4756-5p ; hsa-mir-4459 ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-4779 ; hsa-mir-425-3p ; hsa-mir-7159-5p ; hsa-mir-505-3p ; hsa-mir-625-5p ; hsa-mir-6780b-5p ; hsa-mir-4271 ; hsa-mir-4725-3p ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-6861-3p ; hsa-mir-3202 ; hsa-mir-6790-3p ; hsa-mir-3179 ; hsa-mir-3065-5p ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-3649 ; hsa-mir-4734 ; hsa-mir-6752-3p ; hsa-mir-7106-3p ; hsa-mir-7113-3p

Nearest miRNA

hsa-mir-10b/Upstream/790620; hsa-mir-3133/Downstream/231196;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/6614, chr2-CpG: 117/Downstream/25165

Upstream sequence

CAGTAGCCTGGATTGAAAGGTGCAATCTTCCACATCAGCCTGCGCTGGCCCAATGACCCTGCGTGACTCAACCCCAGGCTCAATCTTAGAGGCTGTTAGA

Downstream sequence

GATTTTACTGGAGGATCTCCATTAGAAAACATCTCCCATTACCAGGTCTTTCTGAATAGACAGAATCCTGCTCCGGGCAGCTTCGCAGTTGGCTCGCTTG