Basic Information
VIS ID
TVIS44007023
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q28.2
Reference genome
GRCh37/hg19
Start
129145635/128224480 (Hg38)
End
129145635/128224480 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/2717173; hsa-mir-1305/Downstream/15118980;
Nearest TSS
ENST00000502981/Upstream/45133; ENST00000505133/Downstream/48581;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/162157, chr4-CpG: 133/Downstream/62662
Nearby gene
LARP1B(+13337) ;
Upstream sequence
TCCAGGGAATGGAACTGTATATGAGATTGAAGTATGGTTATAGCTAAACATACTTGCTTGATTTTTTAAAGCTTTACACAGTTGATTCAGGGTAATTATT
Downstream sequence
GTGTTATCTTTGGGGGATTCTTGATCCTGAACAAAGCTTCATTGTTAGTACTACTACGTTAAAAGTCCTATTGAGTGAAACAGAGGATATAGTCTAATTC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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