Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene9295859292410256926608639265484892679141926759569268825492639439926431349263445592636327926767979267704792684424
Basic Information
VIS ID
TVIS44007039
Fusion event
HTLV-1-LOC105379082 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
92020131/92684424 (Hg38)
End
92020131/92684424 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5B ; FRA5D
Target gene
LOC105379082
Nearest miRNA
hsa-mir-10397/Upstream/2667704; hsa-mir-103a-1/Downstream/936272;
Nearest TSS
ENST00000502646/Upstream/14554; ENST00000502383/Downstream/3830;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/1303311, chr5-CpG: 183/Downstream/886109
Nearby gene
NR2F1-AS1(No orient, 724931)
Upstream sequence
ACATTAGGATATAAATACATGTTTATTGCAAAAAAATTAGAAATAAAACACGTATAATTTCACTCTACCAAGGTAAAACTACTGTTTATATGTGAATATA
Downstream sequence
TATAGTTTCAGGGTTTTTATCTATGTGTATAGATTGGATTAATATTTAATTAGATCACAGATATACAGTTAGGAACATGATAGAATAAATGGTGAATACA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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