VISDB Viral Integration Site DataBase

VIS ID

TVIS44007060

Fusion event

HTLV-1-DLC1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr8

Cytoband

p22

Reference genome

Start

End

13406335/13548826 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-186-5p ; hsa-mir-16-5p ; hsa-let-7d-5p ; hsa-mir-877-3p ; hsa-mir-30c-5p ; hsa-mir-20a-5p ; hsa-mir-200a-3p ; hsa-mir-200b-3p ; hsa-mir-200c-3p ; hsa-let-7a-2-3p ; hsa-let-7g-3p ; hsa-mir-5683 ; hsa-mir-1273e ; hsa-mir-4668-5p ; hsa-mir-3148 ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-6828-5p ; hsa-mir-5688 ; hsa-mir-646 ; hsa-mir-495-3p ; hsa-mir-548c-3p ; hsa-mir-8065 ; hsa-mir-203a-3p ; hsa-mir-3163 ; hsa-mir-4496 ; hsa-mir-5680 ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-340-5p ; hsa-mir-4450 ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-6836-5p ; hsa-mir-6132 ; hsa-mir-1205 ; hsa-mir-511-3p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-576-3p ; hsa-mir-4325 ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-4671-3p ; hsa-mir-633 ; hsa-mir-3976 ; hsa-mir-2278 ; hsa-mir-301a-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-130b-3p ; hsa-mir-3666 ; hsa-mir-130a-3p ; hsa-mir-4295 ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-6754-3p ; hsa-mir-197-3p ; hsa-mir-412-3p ; hsa-mir-1266-3p ; hsa-mir-3140-5p ; hsa-mir-6823-5p ; hsa-mir-4733-3p ; hsa-mir-1226-3p ; hsa-mir-6753-5p ; hsa-mir-578 ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-744-3p ; hsa-mir-29b-2-5p ; hsa-mir-6839-3p ; hsa-mir-4507 ; hsa-mir-3940-5p ; hsa-mir-6740-5p ; hsa-mir-5087 ; hsa-mir-4778-3p ; hsa-mir-483-3p ; hsa-mir-429

Nearest miRNA

hsa-mir-124-1/Upstream/821522; hsa-mir-10400/Downstream/1304612;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/272035, chr8-CpG: 87/Downstream/1687902

Nearby gene

C8orf48(No orient, 18017)

Nearest cancer related gene

DLC1(TSG, No orient, 0)

Upstream sequence

CTAAGACCACCTGTTAATAAACATCAAGATAGCCAGTAAAGAAACAAAATCAAGCTTATTTGGGTTGGTATTATTGTTGATTAATTTCTTAGCTGAGCCA

Downstream sequence

TAGGGAAGATCACTTACATTTCTGACAACAGAATTTCTCTTTTTAGAAAATACTGCTCTGGGCTCCAGAAAAATGTTGGCATGAATTCAGTGGAAGATCA