Basic Information
VIS ID
TVIS44007062
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
43407107/43551964 (Hg38)
End
43407107/43551964 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/655689; hsa-mir-10400/Downstream/18162824;
Nearest TSS
ENST00000518652/Upstream/355796; ENST00000518278/Downstream/3270273;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/274629, chr8-CpG: 41/Downstream/3065403
Upstream sequence
ttggggaatcaaatcattgattcttcagttataccaagggggttatactcggttctgagatacataagtttgacagaagctatgcactgttttacaaagt
Downstream sequence
taaggaaccaatttaacatacaagtcctgaagattaaacttaacaagaggaggagaaggggtcctgccagtacagtaatcagaatagttagccatggatt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate