Basic Information
VIS ID
TVIS44007066
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
99392460/98380232 (Hg38)
End
99392460/98380232 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA8B
Nearest miRNA
hsa-mir-12123/Upstream/3307236; hsa-mir-10400/Downstream/13413;
Nearest TSS
ENST00000518652/Upstream/85839; ENST00000521839/Downstream/8015;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/85734, chr8-CpG: 194/Downstream/46232
Nearby gene
KCNS2(+46790) ;
Upstream sequence
gctgggtagggttagggggtggtgcagatgtggagttactaattaacaggtgtaagttttcagttaagcaaggtgaatacgctctacgttcctctgtacc
Downstream sequence
cacagtcaacaataatgtattgtacacttattacggggatagaaatcatgttaagtgttcttaccacaataaaataaattttaaaaaggaaaagcaaaaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate