Basic Information
VIS ID
TVIS44007165
Fusion event
HTLV-1-ZBED4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
50268257/49874609 (Hg38)
End
50268257/49874609 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZBED4
miRNAs that regulate target gene
hsa-mir-484 ; hsa-mir-98-5p
Nearest miRNA
hsa-let-7a-3/Upstream/331143; hsa-mir-12114/Downstream/88257;
Nearest TSS
ENST00000624155/Upstream/20767; ENST00000610245/Downstream/27619;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/17744, chr22-CpG: 26/Downstream/11782
Upstream sequence
caagtagctgggattacaggggcccaccaccatttttgtatttttagtagacatgggatttcaccagtttggccaggatgctcttgatctcctgacctcg
Downstream sequence
tgatccagctgccttggcctcccgaagtgctgggattacaggcgtgaaccaccatgcccagccttttttttttttttttttttttttttgagacggagtc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate